The nanOXill system has been designed for dry cold nebulization / atomization that does not alter the nature and effectiveness of the active ingredients. This type of dispensing makes it compatible with multiple substances with sanitizing power according to the indications of the various competent bodies. In any case, the device is designed and manufactured for use only with the solutions that are provided by the manufacturer and which are currently based mainly on two active ingredients:

• Hydrogen peroxide
• Sodium hypochlorite

The choice of the most suitable product depends on the environment to be treated, the type of service required and the training of the operator who performs it.

It is not possible to use the nanOXill system with substances other than those supplied by the manufacturer.

In addition to the extensive scientific documentation for the use of the active ingredients used, the nanOXill system has been carefully tested on relevant environments to assess the efficacy of the abatement power of the main contaminants.

Given the importance of the health sector, two environments in which the effectiveness of NanOXill was carefully verified, i.e:

• Diagnostic ambulatory with dimension of about 10 square meters and an approximate volume of 30 cubic meters.

• Surgical ambulatory with an area of about 30 square meters and an approximate volume of 90 cubic meters.

The presence of contaminants was detected through sampling carried out according to the EN ISO 14698: 1-2: 2004 standards and the Standard Safety and Hygiene Guidelines of the ISPESEL (Operating Department).

In both tested environments, samples were carried out on selected surfaces to detect the concentration of fungi and bacteria both before treatment and after a first and second treatment session with a solution containing hydrogen peroxide.

Pickup points

Diagnostic ambulatory: 

• Bed
• Doctor’s chair
• Air inlet nozzle (ventilation system)
• Air extraction nozzle (ventilation system)
• Door handle
• Sink
• Floor
• Wall
• Cabinet handle

Surgical ambulatory: 

• Operating bed
• Operating light handle
• Air inlet nozzle (ventilation system)
• Air extraction nozzle (ventilation system)
• Instruments trolley
• Wall
• Floor
• Doctor’s chair
• Cabinet handle

RESULT SUMMARY

On multiple sampling points there is a significant reduction of the bacterial load already after the first treatment, even in some critical points for contamination and position.

SOME BIBLIOGRAPHICAL INFORMATION ON THE ACTIVE INGREDIENTS OF NANOXILL

The table below shows the main activities of the active ingredients used in the nanOXill sanitation system and for each of them there are shown bibliographic references.

1. Chemical Disinfectants. Guideline for Disinfection and Sterilization in Healthcare Facilities. Centers for Disease Control and prevention. CDC 24/7. 2008.1. Chemical Disinfectants. Guideline for Disinfection and Sterilization in Healthcare Facilities. Centers for Disease Control and prevention. CDC 24/7. 2008.
2.  Dembinski JL. et al. Hydrogen Peroxide Inactivation of Influenza Virus Preserves Antigenic Structure and Immunogenicity. J Virol Methods. 2014; 207:232-7.
3. Jung WK. et al. Antibacterial Activity and Mechanism of Action of the Silver Ion in Staphylococcus aureus and Escherichia coli. APPL. ENVIRON. MICROBIOL. 2008; 74 (7): 2171-2178
4. Silvestry-Rodriguez N. et al. Silver as a disinfectant. Rev Environ Contam Toxicol. 2007; 191: 23-45.
5. Zhukov A. Silver Against the Coronavirus Epidemic. Journal of Education, Health and Sport. 2020; 10(3):83-97.
6. Fukuzaki S. Mechanisms of Actions of Sodium Hypochlorite in Cleaning and Disinfection Processes. Biocontrol Science. 2006; 11 (4): 147-157.
7. Weber D.J., Barbee S.L., Sobsey M.D., Rutala W.A. The effect of blood on the antiviral activity of sodium hypochlorite, a phenolic, and a quaternary ammonium compound. 199; 20-(12): 821-827.

The substances supplied by the manufacturer have been developed by companies with considerable experience in the production of biocompatible and environmentally compatible chemicals. Some of the proposed substances are registered biocides, others are certified as class I medical devices.

NanOXill provides for the use of only high-value raw materials with several quality controls performed in production and before shipment limiting the introduction of chemical components into the environment.

The products used in the NanOXill method have a label registered and validated at the “Istituto Superiore Sanità”, giving the user the guarantee of safe and validated products. It is necessary to pay close attention to the use of unverified substances that can cause significant damage to health. For further information see the article  https://cnsc.iss.it/?p=2727 (italian only)

The solutions proposed for the nanOXill system contain components that are completely compatible with the environment and biodegradable. No detectable residues are released into the treated environment especially if adequate ventilation is performed. In addition, the sanitation performed with an extra fine atomizer allows the air to be sanitized differently from what is possible to achieve with common cleaning procedures manually performed even if they are a good sanitary practice. Dry fog sanitation is a method of containing contaminants that involves a relatively low release of the amount of active ingredients in the environment with the same effectiveness as other sanitation systems, making the system particularly compatible with the environment.